Swine Dysentery

Experimental swine dysentery: comparison between infection models.

The aim of the present study was to develop a reproducible porcine infection model with Brachyspira hyodysenteriae. The influence of different factors was evaluated, namely, age, a diet containing large quantities of soybean meal, housing and administration of cortisol or antacids. Furthermore, the synergistic effect of additional bacteria (Escherichia coli O141, Bacteroides vulgatus or a mixtu...

Prevention of Swine Dysentery with Fitobiotics

An effective method was elaborated for extracting the active substances from commercially available Garden thyme and carob seeds. The antibacterial activity of dilutions of thyme and carob extracts and their combinations were studied by taking the minimum inhibitory concentrations (MIC) with agar well diffusion technique. The most effective concentrations of the two herb extracts were used for ...

A reverse vaccinology approach to swine dysentery vaccine development.

Swine dysentery (SD) is a mucohaemorrhagic colitis of pigs resulting from infection of the large intestine with the anaerobic intestinal spirochaete Brachyspira hyodysenteriae. Whole-cell bacterin vaccines are available to help control SD, but their performance has been inconsistent. This study aimed to use a reverse vaccinology approach to identify B. hyodysenteriae proteins for use as recombi...

Environmental Contamination is a Major Contributor to Prevalence of Serpulina hyodysenteriae Infection of Swine on Farms Medicating Against Swine Dysentery

Immunological alterations during the clinical and recovery phases of experimental swine dysentery.

The aim of this study was to examine changes in the systemic immune response during the incubation period and following the onset of clinical swine dysentery, including the recovery period. Ten healthy conventional pigs were inoculated with Brachyspira hyodysenteriae. Blood was sampled at pre-inoculation, at days 4 and 14 post-inoculation, during the first 4 days with clinical signs of dysenter...